Here are the PDF lecture notes from a single semester liquid state Nuclear Magnetic Resonance (NMR) course I gave at the Weizmann Institute of Science, 2014. These are rough preliminary drafts, so they’re not as comprehensive as I’d like them to be, and there are of course the inevitable typos, sign errors and whatnot. If you do use them, please let me know, and if you find any errors send me an email so I can correct them.
Synposis: Liquid state NMR studies the bulk properties of chemical samples in solution. Many atoms have nuclear magnetic moments which give off and are affected by magnetic fields. Thus, we can “speak to” the moments by generating magnetic fields in the lab by passing current through coils, and we can “listen to” the spins by letting their magnetic fields induce currents in receiver coils. It turns out that the nuclear magnetic moments are very sensitive to their chemical environment within the molecule, including electronic configuration, molecular motion and conformation, chemical bonding and more. This makes NMR an interesting and capable tool for probing many interesting bulk molecular phenomena. These lecture notes examine some of the most common uses of NMR.
Lecture Number | Author | Topic | Link |
|---|---|---|---|
| 1 | Assaf Tal | Basic Spin Physics | PDF |
| 2 | Assaf Tal | The Pulse-Acquire Experiment | |
| 3 | Assaf Tal | Practical 1D NMR | |
| 4 | Assaf Tal | Quantum Mechanics | |
| 5 | Assaf Tal | J-Coupling | |
| 6 | Assaf Tal | Relaxation | |
| 7 | Assaf Tal | 2D NMR | |
| 8 | Assaf Tal | Chemical Exchange |